Modeling VPS13B Lipid Transport Dysfunction in Cohen Syndrome Using Brain Organoids and Retinal Models

Project Description

This project will investigate how the VPS13B protein (the protein affected in Cohen syndrome) functions in brain and retinal cells. Using advanced laboratory models that closely mimic human tissue, the researchers aim to better understand how changes in VPS13B lead to the neurological and vision challenges experienced by people with Cohen syndrome. Their findings may help identify future therapeutic targets.